Neur 604: Ethics in Scientific Research

Wed 12:00 - 2:45, Krasnow Institute, Room 229

Avrama Blackwell

avrama@gmu.edu, 703 993-4381

Office Hours: Wed 3:00 - 4:30, Krasnow Institute, Room 220


GOALS

            To learn how to use major ethical and moral principles to exam ethical issues in scientific research. To provides skills for survival in scientific research through training in moral reasoning, and teaching of responsible conduct. Students learn to apply critical thinking skills to the design, execution and analysis of experiments and to the analysis of current ethical issues in research. Such issues include the use of animals and humans in research, ethical standards in the computer community, and research fraud. In addition, currently accepted guidelines for behavior in areas such as data ownership, manuscript preparation, and conduct of persons in authority are presented and discussed in terms of relevant ethical issues.


READING AND REFERENCE MATERIALS:

Scientific Integrity, Francis L. Macrina, ASM Press, 3rd Edition

Ethics and Computing, Kevin W. Bowyer, IEEE Press, 2nd Edition

Current Journal Articles


GRADING AND COURSE REQUIREMENTS

            Each class consists of lecture, and discussion of cases from text and current articles from journals and newspapers. Students are expected to participate in class discussions.

            Homework consists of reading the assigned chapter prior to class, reading at least one case in the text, and preparing a written summary of the issues for that case from which you could make an oral presentation. Written summaries will be collected every week. Each student will be expected to present a case orally once every three to four weeks.

            The final project is to prepare and present (orally and written) a position paper on a current ethical issue at the end of the semester.


GRADING:

Written summaries: 20% (Late summaries will not be accepted.)

Class participation, including presentation of cases: 10%

Project: 70%

              Project topic and list of resources: 5%, Due 04/04

              Outline of project: 5%, Due 04/11

              Expanded outline (with topic sentences): 15%, Due 04/18

              Final project: 45%, Due 05/02

                        Written (25%)

                        Oral (20%)

The purpose of the project topic and outlines is to help students organize their projects, and to provide feedback both on content and writing style. Late topics and outlines will be accepted, but will be marked down one letter grade for each day late.



SYLLABUS

Week

Topic

Reading

1

01/24

Introduction, requirements for position paper, major moral and philosophical principles for analyzing ethical issues (Guest Lecturer: Dr. Ted Kinnamen from the Department of Philosophy)

Macrina 1, 2
Bowyer 1

2

01/31

Critical thinking skills (Guest Lecturer: Dr. Daniel Rothbart from the Department of Philosophy)

Macrina 2
Bowyer 2

3

02/07

Research fraud; record keeping
PowerPoint Slides

Macrina: 11
news article 1; 2
Paper

4
02/14

SNOW DAY

5

02/21

Responsibilities of persons in authority: mentors, peer reviewers
PowerPoint Slides

Macrina 3, 4
Paper

6

02/28

Issues of gender and race discrimination
PowerPoint Slides

Bowyer 10
Paper

7

03/07

Manuscript preparation: authorship; collaborations
PowerPoint slides

Macrina 4, 8
Paper

8

03/21

Use of humans in research (Guest Lecturer: Sandy Sanford from Office of Sponsored Programs)

Macrina: 5
Paper

9

03/28

Ethical standards in the computer community: hacking, trust, and computer system security (Guest Lecturer: Dr. Ken De Jong from Computer Science Department)

Bowyer: 4

10

04/04

Use of animals in research; computers in safety critical systems
PowerPoint slides

Macrina: 6, Bowyer 6
News1, News2, News3

11

04/11

Conflicts of interest; whistle-blowing
PowerPoint slides

Macrina: 7, Bowyer 7
Paper

12

04/18

Intellectual property; ownership of data and research tools
PowerPoint slides

Macrina: 9, Bowyer 8
Paper1, Paper2

13

04/25

Genetic Technology, Stem Cell research (Guest Lecturer: Dr. Harold Morowitz from the Krasnow Institute)

Macrina 10

14

05/02

Presentation of projects by students