The Krasnow Institute for Advanced Study, of George Mason University

George Mason University

Krasnow Institute > Monday Seminars > Abstracts

Regulation of axon guidance and terminal arbor formation
in the developing CNS

Barry Condron
Assistant Professor, Associate Director Neuroscience Program, Department of Biology, University of Virginia

One of greatest challenges remaining for modern science is to understand how neurons form precise connected networks in the brain. Understanding the formation of connections in the brain will greatly help us to aid the regeneration of damaged or diseased brains. Prior to forming precise connections, neurons form complex tree-like structures of fine cellular processes to sample as many candidate connections as possible. Our research focuses on developing an experimental approach such that genetically altered fruit fly neurons will form branch structures in a way that can be easily manipulated. We wish to dissect the molecular basis for how neurons make complex branch structures both in the developing CNS and potentially be used for future regenerative treatments.

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