The Krasnow Institute for Advanced Study, of George Mason University

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Krasnow Institute > Monday Seminars > Abstracts

Functional Roles for short-term synaptic plasticity

Amitabha Bose

Department of Mathematical Sciences, New Jersey Institute of Technology .

Short-term synaptic plasticity (STSP) refers to a synapse's ability to change its strength as a function of usage. Synapses of this type exist widely throughout the central nervous system. In this talk, I will show that networks that contain synapses which exhibit STSP have several advantages over networks that do not. Working with mathematical models and simulations on problems drawn from different applications of neurobiology, I will discuss how STSP aids in synchronization of hippocampal networks, in maintenance of phase relationships in central pattern generating networks, and in the formation of episodic bursting in ventilatory networks.

 

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