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Krasnow Institute > Monday Seminars > Abstracts Wiring up the Model: Jim Olds Computational neuroscience is dependent upon high fidelity of models. This is particularly true for a structure as complex as the mammalian hippocampal formation. Our recent work on a large scale hippocampal model has emphasized biological realism in both the physiological and anatomical dimmensions. This talk will focus on the anatomical side of that effort. We will define the concept of Minimal Functional Unit (MFU). Using the MFU as a goal for delineating the neuronal constituents of our model, we will then explore constraints on both axons and dendrites and finally propose a strategy for achieving high fidelity, both at the level of cytoarchitectures and in the connectivity matrix for the MFU.
The Krasnow Institute for Advanced Study |
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