This is the official L-Neuron Web Page

L-Neuron is one of the scientific projects of the Computational Neuroanatomy Group at the Krasnow Institute for Advanced Study. We expect to release a first version of L-Neuron in the year 2000, for both DOS/Windows and Unix environments. We will post on this page the software, the manual, a library of the virtual neurons, their morphological analysis, and any news regarding L-Neuron. Until the date of the first release, this is to be considered a temporary page.

Both L-Measure and L-Neuron are now released!

... And the database itself (pre-alpha version -- first alpha release planned for 7/00).

If you want to learn more about the L-Neuron project, see the power-point presentation (click here). If you want to learn more about the Computational Neuroanatomy Group, please click here. If you wish to contact the L-Neuron Principal Investigator, please email Giorgio Ascoli at

The L-Neuron Project is supported by the Krasnow Institute for Advanced Study and by Human Brain Project/Neuroinformatics research grant R01-NS39600-01 (Generation and description of dendritic morphology) awarded in 1999 to Giorgio Ascoli and funded jointly by the National Institute of Neurological Disorders and Stroke and the National Institute of Mental Health (National Institutes of Health).

These motoneurons were simulated by L-Neuron using the algorithms by Hillman (purple, left), Tamori (blue, center), and Burke (green, right). In Hillman’s models, diameters are calculated with Rall’s power rule, while angles are measured empirically. In Tamori’s model, both diameters and angles are calculated. In Burke’s model, both diameters and angles are measured empirically.

A prototype of the user-friendly interface for L-Neuron (windows version, under development).

Giorgio Ascoli sitting in front of an L-Neuron screen view on a Pentium-class computer running Windows 95. Credit: George Mason University (photograph by Tom LeGro).

since June 15, 2000