Axo-axonic or chandelier cells (DG cc)

Main references (data with "?" refer to a reasonable guess; with "??" to a total guess):
Morphology: Freund and Buzsaki, 1996, and references therein.
Number and connectivity: Patton and McNaughton, 1995.
Biochemistry and physiology: Assumed the same as for basket cells.

Type: Interneurons, inhibitory (GABA)
Number: 1000
Location (Dentate Gyrus): soma and axon in granule layer, dendrites in hilus and (rarely) molecular layer.

Explicit morphological data: To be modified from basket cells.

Notes: Although cc synpase onto the axonal initial segment, it might be convenient consider them a sub-class of basket cells. A typical physiological feature is that DG cc often spike doublets.


Axonal output (number of cells contacted, with one synapse unless specified; in parenthesis: number of cells of that type):
6000 DG gc x8 (1000,000)
180 DG mc x8 (30,000) [Freund and Buzsaki, 1996, report no connections]

Axo-somatic input:
?? DG bc?
?? DG cc?
GABA ?350 SHP on soma and dendrites (climbing)

Dendritic input:
Glu 800 DG gc (1,000,000) on shaft?
Glu 1000 DG mc (30,000) on shaft? [Freund and Buzsaki, 1996, report no connections]
Glu 1000 EC (200,000) on shaft?
GABA 200? DG mopp (10,000) on shaft? [Freund and Buzsaki, 1996, report no connections]

Spines: ??
Dendrites: AMPA, NMDA?, CCa, ?
Soma: GABA-A?, GABA-B, CNa, CK?, ED, ?
Axon: ?, CNa, CK?, EP, EC.

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