Axo-axonic or chandelier cells (CA1 cc)

Main references (data with "?" refer to a reasonable guess; with "??" to a total guess):
Morphology: Same as DG cc?
Number and connectivity: Bernard and Wheal, 1994.
Biochemistry and physiology: Freund and Buzsaki, 1996.

Type: Interneurons, inhibitory (GABA)
Number: 1000
Location (CA1): Soma and axon in pyramidal layer, dendrites in all layers.

Explicit morphological data: Same as DG cc?

Notes: Martinez et al. (1996) describe cc regional variability and synaptic targets in DG and CA.
 

Connectivity:

Axonal output (number of cells contacted, with one synapse unless specified; in parenthesis: number of cells of that type):
40,000 CA1 pc x20 (200,000)
800 CA1 bc (4000)

Axo-somatic input:
GABA ?550 SHP on soma and dendrites (climbing)
GABA 800 CA1 bc (4000)
GABA 800 CA1 oa (4000)

Dendritic input:
Glu 12,000 CA3 pc (200,000) on shaft
Glu 90,000 CA1 pc (300,000) on shaft
 

Biochemistry:

Dendrites: AMPA, CCa?, NMDA?
Soma: GABA-A?, GABA-B, CNa, CK?, ED ?
Axon: CNa, CK?, EC, EP.
 

Back to the Main Page