Axo-axonic or chandelier cells (CA3 cc)

Main references (data with "?" refer to a reasonable guess; with "??" to a total guess):
Morphology: Same as DG cc?
Number and connectivity: Bernard and Wheal, 1994.
Biochemistry and physiology: Freund and Buzsaki, 1996.

Type: Interneurons, inhibitory (GABA)
Number: 1000
Location (CA3): Soma and axon in pyramidal layer, dendrites in all layers.

Explicit morphological data: Same as DG cc?

Notes: Martinez et al. (1996) describe cc regional variability and synaptic targets in DG and CA.
 

Connectivity:

Axonal output (number of cells contacted, with one synapse unless specified; in parenthesis: number of cells of that type):
60,000 CA3 pc x20 (200,000)
1200 CA3 oi (4000)

Axo-somatic input:
GABA ?100 SHP on soma and dendrites (climbing)

Dendritic input:
Glu 20,000 CA3 pc (200,000) on shaft
Glu ?? DG gc (1,000,000) on shaft
GABA 800 CA3 ri (4000) on shaft in radiatum
GABA 800 CA3 oi (4000) on shaft in oriens

Biochemistry:
 
Dendrites: AMPA, CCa?, NMDA?
Soma: GABA-A?, GABA-B, CNa, CK?, ED ?
Axon: CNa, CK?, EP, EC.
 

Back to the Main Page