Oriens interneurons (oi)

Main references (data with "?" refer to a reasonable guess; with "??" to a total guess):
Morphology: Same as basket cells?!
Number and connectivity: Bernard and Wheal, 1994.
Biochemistry and physiology: Freund and Buzsaki, 1996.

Type: Interneurons, inhibitory (GABA)
Number: 4000
Location (CA3): Soma in stratum oriens, axons in distal stratum radiatum (lacunosum) dendrites in all layers.

Explicit morphological data: Southampton archive (cells l18, l82 etc.)

Notes: These interneurons are assumed to be dendro-specific basket cells.


Axonal output (number of cells contacted, with one synapse unless specified; in parenthesis: number of cells of that type):
120,000 CA3 pc (200,000) *only 17,000, and just on distal apical dendrites, according to Freund and Buzsaki, 1996*
800 CA3 oi (4000)
200 CA3 cc (1000)

Axo-somatic input:
GABA 290 CA3 cc (1000) on axon
GABA 550 SHP on soma and dendrites (climbing)

Dendritic input:
Glu ?? DG gc (1,000,000) on shaft
Glu 20,000 CA3 pc (200,000) on shaft
GABA 800 CA3 ri (4000) on shaft

Spines: ?
Dendrites: AMPA, CCa?, mGlu, NMDA?
Soma: GABA-A?, GABA-B, CNa, CK?, ED
Axon: CNa, CK?, EC, EP.

Back to the Main Page